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Evexia Science Blog – Justin Bosley BSc Nutritional Science, BSc Chemistry – September 23, 2023

Strongest Antiviral Essential Oils (According to Science)

Plants produce chemical compounds to protect themselves and stay healthy. Many plants produce volatile (quickly evaporating) oils. We call them essential oils because they contain the essence of the plant and are essential to the health of the plant. Without these oils, the plant would quickly succumb to diseases. It is very remarkable how versatile these little compounds are. They can work as deterrents to bugs, many different bacteria, and even viruses!

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Evexia Science Blog – Justin Bosley BSc Nutritional Science, BSc Chemistry – April 01, 2024

Dental Plaque: The Silent Threat to Your Smile

Hey there! You might not realize it, but your smile could secretly be under attack. That sticky film that builds up on your teeth - yup, that gross plaque - is actually a big threat to your oral health. Plaque might seem harmless, but it can wreak havoc if you don't remove it regularly. The good news is you can fight back and protect your pearly whites with some simple plaque-removal tricks. Stick with me and you'll learn how getting rid of more plaque can transform your smile for the better. Even small changes to your routine can make a huge difference, so let's talk about how to defeat plaque once and for all! What Is Dental Plaque Many people seem to accept that plaque is a normal part of life and just focus on brushing their teeth. The truth is, that plaque buildup is dangerous to your oral health and smile. Plaque is a sticky, colorless film of bacteria that forms on your teeth and along the gum line. If left unattended, plaque hardens into tartar, which can only be removed by a dental professional. The Effects of Plaque Buildup on Your Teeth and Gums Plaque is that sticky, colorless layer of bacteria that forms on your teeth and gums. While it may seem harmless, plaque buildup can wreak havoc on your oral health over time. Gum disease. As plaque builds up along your gum line, it causes inflammation and irritation. Left untreated, this can advance to periodontitis, a serious gum infection that damages the soft tissue and bone supporting your teeth. Warning signs include swollen, red gums, persistent bad breath, and loose or shifting teeth. Tooth decay. The bacteria in plaque produce acids that break down the enamel on your teeth. This results in cavities, which get bigger over time and may require fillings or crowns to repair the damage. Cavities often don’t cause any symptoms until they get quite large, so regular dental exams are critical to catching them early. Bad breath. The bacteria in plaque release foul-smelling gases, especially in areas that are hard to reach with your toothbrush. Removing plaque through brushing, flossing, and professional cleanings helps eliminate the causes of bad breath and leaves your mouth feeling fresh. Stained or yellow teeth. As plaque builds up on your teeth over days and weeks, it causes surface stains that make your teeth look dull or yellow. Thorough plaque removal helps prevent staining and keeps your smile bright and white. How to Remove Plaque Effectively The most effective way to remove plaque from your teeth is through daily brushing and flossing. Brushing removes plaque from the surfaces of your teeth, while flossing removes plaque between teeth where the toothbrush can’t reach. Floss at Least Once Per Day Flossing removes plaque and food particles from between your teeth which the toothbrush can’t reach. Floss at least once per day, preferably at night before bed. Brush Your Teeth Twice a Day You should brush your teeth at least twice per day for two minutes each time, preferably after every meal. Pay extra attention to brushing along the gum line and hard-to-reach areas in the back of your mouth. Use a soft-bristled brush. Brush your teeth at a 45-degree angle to your gums. Brush with The Honest Tooth The Honest Tooth is a tooth powder that is designed to get your teeth cleaner and whiter, and your breath fresher than normal toothpaste. The Honest Tooth can remove all four causes of dental issues: plaque, bacteria, food debris, and tooth-eating acids. It works much better than normal toothpaste. It does this through several key ingredients. Baking soda – Baking soda helps to neutralize tooth-eating acids as well as gently polish your teeth to remove plaque. Xylitol – xylitol is a natural sugar-alcohol derived from birch trees. It helps to kill bacteria that cause tooth decay such as S. mutans. Monolaurin – Monolaurin is a fat that is enzymatically derived from coconut oil. It helps to dissolve the plaque and remove it from the hard-to-reach areas and grooves in your teeth and gums. Cinnamon and clove essential oils – Have been scientifically proven to kill s. mutans, the bacteria that causes cavities. The Benefits of The Honest Tooth Cleaner teethA whiter smileFresher breathReduced risk of gingivitisReduced risk of cavities   Get your bottle today! Use the code Evexia10 to get 10% off your order! Conclusion So in summary, plaque is a sneaky thing that can ruin your beautiful smile before you even realize it's there. Don't let it creep up on you! Make plaque your enemy and fight it daily with good brushing and flossing habits, and use The Honest Tooth. Your pearly whites will thank you. Remember, plaque is always ready to attack, so be vigilant. But you've got this! With the right tools and techniques, you can send plaque packing. Stay on top of your oral hygiene game and keep that knockout grin. You only get one set of adult teeth, so take good care of them. They're yours for life!

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Evexia Science Blog – Justin Bosley BSc Nutritional Science, BSc Chemistry – April 15, 2024

Fart Less, Live More: Tips for Reducing Gas and Bloating

After you eat, do you feel like you swallowed an air mattress? Your stomach is gurgling and growling, ready to unleash noxious fumes at any moment. It's happened before - the moment of gastrointestinal betrayal when your body rebels, subjecting innocent bystanders to the horrors within. But never fear, there are ways to tame the beast and restore peace to your insides. This article will explore simple tips to improve your gut health and reduce embarrassing gas and bloating. You may not achieve sainthood, but you can aim for basic human decency. We know it isn’t the most glamorous topic, but read on to discover how small changes can lead to good gut feelings all around. The Causes of Excessive Gas and Bloating Simple Sugars Well, folks, the truth is your tummy troubles are likely self-inflicted. Those irresistible candies, cakes, and ice cream you’ve been packing away are packed with sugar that feeds the bacteria festering in your gut. The result? Enough hot air to fuel your backyard BBQ. Your Bad Bacterial Overgrowth That’s right, there’s a whole microbial mosh pit going on in your intestines. When the nasty bacteria get the upper hand, they have a gas-fuelled field day breaking down undigested food and the resultant hydrogen and methane are what’s puffing you up like a balloon. You Talk Too Much Your mama always told you not to talk with your mouth full, but did you listen? No, you insisted on yammering away during dinner, gulping in extra air with every bite. All that excess air has to go somewhere, so it heads straight down to your gut. You’re a Slurper and a Straw-Sucker If you drink carbonated soft drinks or you’re prone to slurping your drinks or sucking them up through a straw, you’re swallowing a bellyful of air. And that air is getting trapped, causing your midsection to inflate like a puffer fish. Dietary Changes That Can Reduce Gas and Bloating Let's face it, some foods just don't agree with our digestive systems. If you find yourself frequently feeling like an overinflated balloon, it may be time to make some dietary changes. The good news is with a few simple fixes like easing up on the gassy grub, improving your eating habits, and taking the right supplements, you’ll be back to your slender and graceful self in no time and enjoying meals without the musical accompaniment. Now that’s something worth tooting your horn about! Increase Your Fiber Intake Slowly Fiber is important for gut health, but too much of a good thing can lead to excess gas. Gradually increase your fiber intake and be sure to drink plenty of water to help the extra roughage move through your system. Some people find relief by switching to less gas-inducing sources, like whole grains over beans. Careful with the Legumes Speaking of beans, lentils, broccoli, and cabbage, limit these notorious gas-causers at first. The more you eat them, the more your digestive system will adapt and you won't produce as many noxious fumes. Watch Your Lactose Your gut bacteria will adjust over time, but take it slow. The same goes for dairy, if you're lactose intolerant. Try lactose-free options or non-dairy milk and yogurts. The Right Supplements Gut Reset, an herbal supplement from Evexia Science, contains berberine and silymarin, which can help improve gut health and ease bloating by potentially reducing gas-producing bacteria in the intestines. Use the code HealthyGut10 to get 10% off today! Products like Beano also contain enzymes to help break down gas-causing compounds in certain foods. While probiotics are great for gut health, some can initially cause excess gas and bloating. Start with a lower dose and build up slowly. The same goes for prebiotics like inulin - moderation is key. Making a few simple diet changes can significantly reduce your gas and bloating, leaving you free to do more of the important things in life - like leaving the room without embarrassment after passing wind! Your gut and those around you will surely thank you. Lifestyle Tips to Improve Digestion and Decrease Gas Eat Slowly, Chew Thoroughly When you wolf down your food like a ravenous beast, you end up swallowing a lot of air with every bite. All that extra air in your gut leads to gas and bloating. Slow down, chill out, and taste your food. Chew each bite 20-30 times to help break it down and release its nutrients. Your stomach will thank you. Stay Hydrated Being dehydrated slows down digestion and can lead to gas and constipation. Aim for 6-8 glasses of water per day to keep your gut happy. Other gut-friendly beverages include peppermint or ginger tea, which can double as a natural digestive aid. If plain water bores you, add some lemon or cucumber for extra flavor and hydration. Electrolytes Staying hydrated with plain water is important, but adding electrolytes can also help reduce bloating and aid digestion. Electrolytes like sodium, potassium, and magnesium help draw water into your gut and keep it hydrated. This hydration helps digestive enzymes work properly and also speeds up transit time, reducing gas and bloating. Some easy ways to get more electrolytes: Drink electrolyte beverages like coconut water or sports drinks in moderation. Start with a small amount and see how your body reacts. Add a pinch of salt to your water. While salt gets a bad rap, the right amount can aid digestion. Just be sure not to overdo it. Eat more potassium-rich foods like bananas, avocados, sweet potatoes, and leafy greens. These high-potassium plant foods also provide fiber to feed your gut bacteria. Drink potassium-rich fruit and vegetable juices such as carrot juice or orange juice. Sprinkle some magnesium-rich foods into your diet like pumpkin seeds, almonds, spinach, and dark chocolate. Magnesium helps relax muscles throughout your digestive tract, easing gas and cramping. Move That Body Exercise helps stimulate bowel movements and improves digestion. Even taking a 30-minute walk can help get your gut moving. Yoga or Tai Chi are also great for reducing stress and relaxing your abdomen. Specific yoga poses like knees-to-chest, cat/cow, and twists can gently massage your intestines and release any pent-up gas. So get off the couch and go move around - your gut will thank you, and the people around you will too! Frequently Asked Questions About Reducing Gas and Bloating Do probiotics really help? Probiotics are supposed to help by adding “good” bacteria to your gut, but whether or not they work depends on the person and the product. Some studies show probiotics may reduce gas and bloating for certain individuals, but for others, they do diddly squat. The good bacteria in most over-the-counter probiotics may not even take up residence in your gut due to all of the other bacteria in there taking up space. Our advice? If you want to make probiotics more effective then you should try using Gut Reset to help clear some of the space for the good bacteria to grow. What about digestive enzymes? Do they reduce gas? Digestive enzymes can help break down food so your gut doesn’t have to work as hard, which may lead to less gas overall. Look for a broad-spectrum enzyme formula containing proteases for protein, lipases for fat, and amylases for carbs. Enzymes won’t solve an underlying issue like SIBO or IBS, but they can provide relief from occasional gas and indigestion. I’ve heard simethicone can reduce gas. Does it really work? Simethicone products like Gas-X contain an anti-foaming agent that helps break up gas bubbles in your gut. For some people, simethicone does seem to provide relief from gas and make passing gas less uncomfortable. However, simethicone just treats the symptoms, it doesn’t actually reduce the amount of gas in your intestines or prevent gas formation. It also may not work for gas caused by certain foods or conditions like SIBO or IBS. Simethicone can be worth trying for occasional gas relief, but for chronic issues, you’ll need to address the underlying cause. Are there any natural remedies that can help reduce gas? Some natural remedies that may reduce gas include: Peppermint or ginger tea: Both are soothing to the gut and have anti-gas properties. Probiotic yogurt: Look for yogurt containing live active cultures like lactobacillus or bifidobacterium. Fennel seeds: Chew on a teaspoon full of fennel seeds after meals to improve digestion and reduce gas. Turmeric: Turmeric has anti-inflammatory effects and may help ease gas and bloating. Try turmeric supplements or adding turmeric to your meals like yellow curry. Berberine and silymarin combined: These two herbs work in synergy to kill bad bacteria and may benefit those with digestive health issues by reducing bacteria in the intestines. This is the active ingredient formula that is found in Gut Reset. Conclusion So there you have it, folks. A few small tweaks to your diet and lifestyle can lead to big improvements in the wind farm situation. We know it's not the most glamorous topic, but a little less toot can mean a lot more spring in your step. This ain't no laughing matter - reducing gas and bloating can seriously enhance your quality of life. And your loved ones will thank you too. So take these tips to heart, stomach, and other affected areas. You've got the power to take control of your hot air supply. It's time to say "see ya" to excess fumes and start feeling - and smelling - like a whole new you. Now go forth and fart less my friends. Your body and your neighbor will thank you. References “Symptoms & Causes of Gas in the Digestive Tract - NIDDK,” National Institute of Diabetes and Digestive and Kidney Diseases. Accessed: Apr. 20, 2024. [Online]. Available: https://www.niddk.nih.gov/health-information/digestive-diseases/gas-digestive-tract/symptoms-causes “Bloated Stomach: Causes, Tips to Reduce & When to be Concerned,” Cleveland Clinic. Accessed: Apr. 20, 2024. [Online]. Available: https://my.clevelandclinic.org/health/symptoms/21740-bloated-stomach “Practical tips to reduce bloating, belching and gas,” Mayo Clinic. Accessed: Apr. 20, 2024. [Online]. Available: https://www.mayoclinic.org/diseases-conditions/gas-and-gas-pains/in-depth/gas-and-gas-pains/art-20044739 “What Is Intestinal Gas?,” Cleveland Clinic. Accessed: Apr. 20, 2024. [Online]. Available: https://my.clevelandclinic.org/health/diseases/7314-gas-and-gas-pain “Gas and gas pains-Gas and gas pains - Symptoms & causes,” Mayo Clinic. Accessed: Apr. 20, 2024. [Online]. Available: https://www.mayoclinic.org/diseases-conditions/gas-and-gas-pains/symptoms-causes/syc-20372709

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Evexia Science Blog – Justin Bosley BSc Nutritional Science, BSc Chemistry – May 06, 2024

Dentures Prevention: Steps You Can Take to Protect Your Gums and Teeth

As you age, your risk of losing teeth increases, but there are ways you can protect your gums and teeth to decrease the chance of needing dentures later in life. Eating a balanced diet, practicing good oral hygiene, brushing your teeth with The Honest Tooth powder, and getting regular dental care are all steps you can take now to support your oral health. Additionally, quitting tobacco use and limiting sugary foods and acidic drinks will help keep your teeth and gums strong. With some diligence regarding your diet and dental care routines, you can maintain your natural teeth for many more years to come. Taking preventive measures today will allow you to continue smiling confidently well into the future. The Importance of Healthy Gums for Avoiding Dentures Healthy gums are essential for maintaining your natural teeth as you age. Gum disease, also known as periodontal disease, is one of the leading causes of tooth loss in adults. As gums become inflamed, they pull away from teeth, exposing sensitive root surfaces and creating pockets where more bacteria can grow. If left untreated, the infection can spread into the bone and ligaments supporting your teeth, eventually causing them to become loose or fall out. Common Causes of Gum Disease as You Age As you get older, your gums become more susceptible to disease. According to the Centers for Disease Control and Prevention (CDC), in the United States, about 68% of adults aged 65 years and older have periodontal disease [1]. Poor Oral Hygiene Not brushing and flossing regularly allows plaque to build up on teeth and gums. Plaque contains bacteria that inflame the gums, causing swelling, redness, and bleeding. [2] Vitamin Deficiencies A balanced diet with plenty of calcium, magnesium, zinc, vitamins C and D is essential for tooth and gum health [3], [4], [5]. Vitamin C helps maintain the integrity of gum tissue, while vitamin D helps your body absorb calcium and magnesium so that you can regenerate bones and teeth. Vitamin D is also important for immune function so your body does not get overrun with harmful bacteria that leads to chronic inflammation. As you age, stomach acid decreases, making it harder to absorb certain nutrients. [6] There is also a strong independent correlation between H. pylori infection and lower stomach acid levels. Talk to your doctor about supplements like betaine HCl for stomach acid, treatments for H. pylori or diet changes to address any deficiencies. Dry Mouth Saliva naturally helps wash away food particles and neutralize plaque acids. However, many older adults experience dry mouth due to medications or health conditions. Drinking electrolyte drinks, chewing xylitol gum, sucking on ice chips, using a humidifier, brushing your teeth with The Honest Tooth and avoiding alcohol or caffeine can help stimulate saliva flow and relieve dry mouth.  Diet and Lifestyle Tips for Healthy Gums Choose Fiber and Antioxidant-Rich Foods Fresh fruits and vegetables high in fiber help clean teeth and gums as you chew, removing built-up plaque and food particles. [7] Apples, carrots, broccoli, and beans are excellent options. Most adults need 25 to 30 grams of fiber per day from whole foods. Antioxidants and bioflavonoids in your diet can help reduce inflammation, promote wound healing, kill bacteria, improve blood flow, and overall, support immune health. Eating foods high in flavonoids such as blueberries, strawberries, purple corn, blue potatoes, and other foods high in purple, red, and blue colors (the color comes from the flavonoids) can help to improve gum health. [8] Limit Sugary and Starchy Foods Excess sugar and refined carbohydrates feed the harmful bacteria in your mouth that destroy gums and tooth enamel. Limit sweets, white bread, pasta, and rice which stick to teeth and are digested quickly into simple sugars. Choose complex carbohydrates like whole grains instead, and rinse your mouth with water within 30 minutes after eating to remove plaque-promoting sugars.  Oral Hygiene Habits That Protect Your Teeth and Gums Floss Daily Flossing removes dental plaque and food particles from between the teeth and under the gumline, where toothbrushes can't reach. Dental plaque contains bacteria that inflame the gums and damage tooth enamel by producing acids which dissolve your teeth. Make flossing a daily habit to prevent gum disease and reduce your risk of tooth loss. [9] Visit Your Dentist Regularly See your dentist for a thorough dental exam and professional cleaning at least twice per year. Your dentist and hygienist can remove built-up tartar from your teeth that you can’t reach at home (unless you brush with The Honest Tooth). They also examine your gums and teeth for signs of damage or disease. Early detection of gum disease or other dental health issues is critical to avoiding tooth loss and more serious complications.  Use a Soft Bristle Toothbrush Choose a toothbrush with soft, rounded bristles that won’t irritate your gums. Medium or hard bristles can damage your gums over time and lead to recession. Look for a toothbrush that has the American Dental Association (ADA) Seal of Acceptance, as these have been tested to properly clean teeth and gums. Be sure to replace your toothbrush every 3-4 months, or sooner if the bristles become frayed. Limit Acidic Foods A diet high in acidic foods and beverages erodes tooth enamel and softens your teeth making it easier for bacteria to invade. Limit colas with phosphoric acid, vinegar-y beverages, and citrus juices. When you do consume these foods and drinks, rinse your mouth with water afterward and avoid brushing for at least 30 minutes. The softened enamel is more prone to damage from brushing right after eating or drinking. [10] Rinsing your mouth with The Honest Tooth after eating acidic foods can also help reduce acid-softening of your teeth. Natural Remedies to Strengthen Gums and Prevent Dentures To maintain your natural teeth as you age, it is essential to keep your gums healthy. Several natural remedies can help reduce inflammation, kill bacteria that lead to gum disease and tooth decay, and strengthen your gums. Brush with Baking Soda Baking soda is a mild abrasive that helps remove plaque and surface stains from teeth. Brushing your teeth with baking soda daily can help re duce plaque buildup that leads to gum disease and tooth decay. The alkalinity of baking soda also helps neutralize acid in the mouth that causes damage to enamel and gums. [11-14] Use Xylitol-Based Products Xylitol is a natural sugar alcohol that helps reduce bacteria in the mouth that lead to plaque, tooth decay, and gum disease. Toothpaste, mouthwash, and oral care products containing xylitol can help improve gum health and reduce inflammation. Xylitol also helps neutralize acid in the mouth to prevent damage to teeth and gums. [15-18] Use Essential Oils Essential oils like cinnamon and clove have natural antimicrobial properties that help kill bacteria in the mouth that lead to gum disease and tooth decay. These essential oils can help reduce inflammation in gums and have been studied to kill the bacteria that lead to tooth decay. [19-23] Use The Honest Tooth The Honest Tooth is a tooth powder with a combination of baking soda, xylitol, cinnamon, and clove essential oils, as well as a special ingredient that fights plaque: monolaurin. The Honest Tooth is scientifically designed to reduce plaque with scientifically proven ingredients to fight tooth decay and gum disease. Monolaurin is our secret ingredient that makes The Honest Tooth remove plaque better than other kinds of toothpaste or tooth powders. It can even remove tarter/calculus, which no other tooth cleaning product can do! It is especially great for getting into places where your toothbrush cannot get and removing plaque from hard-to-reach areas, like braces and retainers! Get your bottle today, with 15% off! Use the code FightPlaque15 at checkout. Conclusion While dentures may seem inevitable as we age, there are proactive steps you can take now to protect your oral health and keep your natural teeth longer. Commit to a daily oral hygiene routine, get regular dental cleanings and exams, and tell your dentist about any changes you notice. Maintain a balanced diet low in sugars and acids that erode enamel. Use The Honest Tooth regularly. With diligence and preventative care, you can boost your chances of maintaining your natural smile well into your golden years. Taking control of your oral health future starts today. References [1] “Oral Health for Older Americans | Adult Oral Health | Basics | Division of Oral Health | CDC.” Accessed: May 06, 2024. [Online]. Available: https://www.cdc.gov/oralhealth/basics/adult-oral-health/adult_older.htm [2] R. J. Genco, “Current View of Risk Factors for Periodontal Diseases,” J. Periodontol., vol. 67, no. 10S, pp. 1041–1049, 1996, doi: 10.1902/jop.1996.67.10s.1041. [3] J. Botelho, V. Machado, L. Proença, A. S. Delgado, and J. J. Mendes, “Vitamin D Deficiency and Oral Health: A Comprehensive Review,” Nutrients, vol. 12, no. 5, p. 1471, May 2020, doi: 10.3390/nu12051471. [4] U. Van der Velden, “Vitamin C and Its Role in Periodontal Diseases - The Past and the Present: A Narrative Review,” Oral Health Prev. Dent., vol. 18, pp. 115–124, Apr. 2020, doi: 10.3290/j.ohpd.a44306. [5] A. Togari, S. Arakawa, M. Arai, and S. Matsumoto, “Alteration of in vitro bone metabolism and tooth formation by zinc,” Gen. Pharmacol., vol. 24, no. 5, pp. 1133–1140, Sep. 1993, doi: 10.1016/0306-3623(93)90360-a. [6] M. Goldschmiedt, C. C. Barnett, B. E. Schwarz, W. E. Karnes, J. S. Redfern, and M. Feldman, “Effect of age on gastric acid secretion and serum gastrin concentrations in healthy men and women,” Gastroenterology, vol. 101, no. 4, pp. 977–990, Oct. 1991, doi: 10.1016/0016-5085(91)90724-y. [7] H. Swarnamali, N. Medara, A. Chopra, A. Spahr, and T. N. Jayasinghe, “Role of Dietary Fibre in Managing Periodontal Diseases-A Systematic Review and Meta-Analysis of Human Intervention Studies,” Nutrients, vol. 15, no. 18, p. 4034, Sep. 2023, doi: 10.3390/nu15184034. [8] I. Nawrot-Hadzik, A. Matkowski, P. Kubasiewicz-Ross, and J. Hadzik, “Proanthocyanidins and Flavan-3-ols in the Prevention and Treatment of Periodontitis-Immunomodulatory Effects, Animal and Clinical Studies,” Nutrients, vol. 13, no. 1, p. 239, Jan. 2021, doi: 10.3390/nu13010239. [9] V. Gupta, A. Dawar, U. S. Bhadauria, B. M. Purohit, and N. Nilima, “Sugar-sweetened beverages and periodontal disease: A systematic review,” Oral Dis., vol. 29, no. 8, pp. 3078–3090, Nov. 2023, doi: 10.1111/odi.14368. [10] T. Saads Carvalho and A. Lussi, “Chapter 9: Acidic Beverages and Foods Associated with Dental Erosion and Erosive Tooth Wear,” Monogr. Oral Sci., vol. 28, pp. 91–98, 2020, doi: 10.1159/000455376. [11] A. T. Hara and C. P. Turssi, “Baking soda as an abrasive in toothpastes: Mechanism of action and safety and effectiveness considerations,” J. Am. Dent. Assoc. 1939, vol. 148, no. 11S, pp. S27–S33, Nov. 2017, doi: 10.1016/j.adaj.2017.09.007. [12] “Baking soda dentifrices and oral health - The Journal of the American Dental Association.” Accessed: Nov. 12, 2021. [Online]. Available: https://jada.ada.org/article/S0002-8177(17)30822-X/fulltext [13] J. A. Cury, L. N. Hashizume, A. A. Del Bel Cury, and C. P. Tabchoury, “Effect of dentifrice containing fluoride and/or baking soda on enamel demineralization/remineralization: an in situ study,” Caries Res., vol. 35, no. 2, pp. 106–110, Apr. 2001, doi: 10.1159/000047440. [14] C. Valkenburg, Y. Kashmour, A. Dao, G. A. Fridus Van der Weijden, and D. E. Slot, “The efficacy of baking soda dentifrice in controlling plaque and gingivitis: A systematic review,” Int. J. Dent. Hyg., vol. 17, no. 2, pp. 99–116, May 2019, doi: 10.1111/idh.12390. [15] V. Ahuja, M. Macho, D. Ewe, M. Singh, S. Saha, and K. Saurav, “Biological and Pharmacological Potential of Xylitol: A Molecular Insight of Unique Metabolism,” Foods, vol. 9, no. 11, p. 1592, Nov. 2020, doi: 10.3390/foods9111592. [16] E. Söderling and K. Pienihäkkinen, “Effects of xylitol and erythritol consumption on mutans streptococci and the oral microbiota: a systematic review,” Acta Odontol. Scand., vol. 78, no. 8, pp. 599–608, Nov. 2020, doi: 10.1080/00016357.2020.1788721. [17] V. Loimaranta, D. Mazurel, D. Deng, and E. Söderling, “Xylitol and erythritol inhibit real-time biofilm formation of Streptococcus mutans,” BMC Microbiol., vol. 20, no. 1, p. 184, Jun. 2020, doi: 10.1186/s12866-020-01867-8. [18] K. Salli, M. J. Lehtinen, K. Tiihonen, and A. C. Ouwehand, “Xylitol’s Health Benefits beyond Dental Health: A Comprehensive Review,” Nutrients, vol. 11, no. 8, p. E1813, Aug. 2019, doi: 10.3390/nu11081813. [19] H. A. Gandhi, K. T. Srilatha, S. Deshmukh, M. P. Venkatesh, T. Das, and I. Sharieff, “Comparison of Antimicrobial Efficacy of Cinnamon Bark Oil Incorporated and Probiotic Blend Incorporated Mucoadhesive Patch against Salivary Streptococcus mutans in Caries Active 7-10-year-old Children: An In Vivo Study,” Int. J. Clin. Pediatr. Dent., vol. 13, no. 5, pp. 543–550, Oct. 2020, doi: 10.5005/jp-journals-10005-1818. [20] K. Ács, V. L. Balázs, B. Kocsis, T. Bencsik, A. Böszörményi, and G. Horváth, “Antibacterial activity evaluation of selected essential oils in liquid and vapor phase on respiratory tract pathogens,” BMC Complement. Altern. Med., vol. 18, no. 1, p. 227, Jul. 2018, doi: 10.1186/s12906-018-2291-9. [21] B. Lapinska et al., “An In Vitro Study on the Antimicrobial Properties of Essential Oil Modified Resin Composite against Oral Pathogens,” Mater. Basel Switz., vol. 13, no. 19, p. E4383, Oct. 2020, doi: 10.3390/ma13194383. [22] M. Khan, H. Z. Alkhathlan, and S. T. Khan, “Antibiotic and Antibiofilm Activities of Salvadora persica L. Essential Oils against Streptococcus mutans: A Detailed Comparative Study with Chlorhexidine Digluconate,” Pathogens, vol. 9, no. 1, p. 66, Jan. 2020, doi: 10.3390/pathogens9010066. [23] K. Wiwattanarattanabut, S. Choonharuangdej, and T. Srithavaj, “In Vitro Anti-Cariogenic Plaque Effects of Essential Oils Extracted from Culinary Herbs,” J. Clin. Diagn. Res. JCDR, vol. 11, no. 9, pp. DC30–DC35, Sep. 2017, doi: 10.7860/JCDR/2017/28327.10668.

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